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T-2 Toxin Induces Epiphyseal Plate Lesions via Decreased SECISBP2-Mediated Selenoprotein Expression in DA Rats, Exacerbated by Selenium Deficiency

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Published in 2018 at "CARTILAGE"

DOI: 10.1177/1947603518809406

Abstract: Objective Both selenium (Se) deficiency and mycotoxin T2 lead to epiphyseal plate lesions, similar to Kashin-Beck disease (KBD). However, regulation of selenoproteins synthesis mediated by SECISBP2, in response to these 2 environmental factors, remained unclear.… read more here.

Keywords: epiphyseal plate; plate lesions; expression; toxin ... See more keywords