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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26483
Abstract: CFTR is a cAMP‐regulated chloride channel, whose mutations produce cystic fibrosis. The impairment of CFTR activity increases the intracellular Cl− concentration, which in turn produces an increased interleukin‐1β (IL‐1β) secretion. The secreted IL‐1β then induces…
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Keywords:
ereg;
epiregulin ereg;
autocrine loop;
reduced cftr ... See more keywords