Heterogeneous brain dynamic functional connectivity patterns in first‐episode drug‐naive patients with major depressive disorder
Sign Up to like & getrecommendations! Published in 2023 at "Human Brain Mapping"
DOI: 10.1002/hbm.26266
Abstract: It remains challenging to identify depression accurately due to its biological heterogeneity. As people suffering from depression are associated with functional brain network alterations, we investigated subtypes of patients with first‐episode drug‐naive (FEDN) depression based… read more here.
Keywords: connectivity; network; first episode; episode drug ... See more keywords
Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: An exploratory pilot case-control study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.01.014
Abstract: BACKGROUND Early intervention in depression has been critical to prevent its negative impact including suicide. Recent blood biomarker studies for major depressive disorder (MDD) have suggested that tryptophan-kynurenine and lipid related metabolites are involved in… read more here.
Keywords: tryptophan kynurenine; mdd; first episode; episode drug ... See more keywords
Sub-regional hippocampal volumes in first-episode drug-naïve major depression disorder
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136178
Abstract: Hippocampal volume reduction was reported to underlie depressive symptomatology, however, the evidence to date remains inconsistent. For the complex intrinsic organization of hippocampus, the hippocampal volumes can be further divided into subfields or axial parts.… read more here.
Keywords: sub regional; first episode; hippocampal volumes; episode drug ... See more keywords
Aberrant perfusion and its connectivity within default mode network of first-episode drug-naïve schizophrenia patients and their unaffected first-degree relatives
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-14343-7
Abstract: Neural substrates behind schizophrenia (SZ) and its heritability mediated by brain function are largely unknown. Cerebral blood flow (CBF), as a biomarker of activation in the brain, reflects the neuronal metabolism, and is promisingly used… read more here.
Keywords: network; connectivity; first episode; episode drug ... See more keywords
Gender difference in vitamin A levels in first-episode drug-naïve depression patients: a case-control and 24-weeks follow-up study.
Sign Up to like & getrecommendations! Published in 2020 at "Die Pharmazie"
DOI: 10.1691/ph.2020.9829
Abstract: Depression is one of the major causes of disability in societies worldwide. However, only a few studies have been conducted to analyze the relationship between vitamin A levels and depression. This study aimed to explore… read more here.
Keywords: first episode; episode drug; vitamin levels; vitamin ... See more keywords
A Meta-Analysis of Abnormal Glucose Metabolism in First-Episode Drug-Naive Schizophrenia.
Sign Up to like & getrecommendations! Published in 2020 at "Psychiatria Danubina"
DOI: 10.24869/psyd.2020.46
Abstract: BACKGROUND Patients with schizophrenia exhibit a higher mortality rate compared with the general population. This mortality has been attributed predominantly by the high risk of type 2 diabetes mellitus in the patients. We aimed to… read more here.
Keywords: schizophrenia; first episode; episode drug; glucose metabolism ... See more keywords
Neural activity changes in first-episode, drug-naïve patients with major depressive disorder after transcutaneous auricular vagus nerve stimulation treatment: A resting-state fMRI study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1018387
Abstract: Introduction Major depressive disorder (MDD) is a disease with prominent individual, medical, and economic impacts. Drug therapy and other treatment methods (such as Electroconvulsive therapy) may induce treatment-resistance and have associated side effects including loss… read more here.
Keywords: first episode; episode drug; treatment; drug ... See more keywords
The Association Between Cognitive Deficits and Clinical Characteristic in First-Episode Drug Naïve Patients With Schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.638773
Abstract: Background: Schizophrenia is a severe mental disease which characterized by positive symptom, negative symptom, general pathology syndrome and cognitive deficits. In recent years, many studies have investigated the relationship between cognitive deficits and clinical characteristics… read more here.
Keywords: symptom; cognitive deficits; first episode; pathology ... See more keywords
Vortioxetine Modulates the Regional Signal in First-Episode Drug-Free Major Depressive Disorder at Rest
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.950885
Abstract: Background Previous studies on brain functional alterations associated with antidepressants for major depressive disorder (MDD) have produced conflicting results because they involved short treatment periods and a variety of compounds. Methods Resting-state functional magnetic resonance… read more here.
Keywords: first episode; vortioxetine modulates; episode drug; drug free ... See more keywords
The Serum Brain-Derived Neurotrophic Factor Increases in Serotonin Reuptake Inhibitor Responders Patients with First-Episode, Drug-Naïve Major Depression
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020584
Abstract: Brain-derived neurotrophic factor (BDNF) is a growth factor synthesized in the cell bodies of neurons and glia, which affects neuronal maturation, the survival of nervous system, and synaptic plasticity. BDNF play an important role in… read more here.
Keywords: serum bdnf; first episode; episode drug; bdnf ... See more keywords