Multimodal MRI assessment for first episode psychosis: A major change in the thalamus and an efficient stratification of a subgroup
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25276
Abstract: Multi‐institutional brain imaging studies have emerged to resolve conflicting results among individual studies. However, adjusting multiple variables at the technical and cohort levels is challenging. Therefore, it is important to explore approaches that provide meaningful… read more here.
Keywords: first episode; multimodal mri; assessment first; mri assessment ... See more keywords
Altered hippocampal centrality and dynamic anatomical covariance of intracortical microstructure in first episode psychosis
Sign Up to like & getrecommendations! Published in 2020 at "Hippocampus"
DOI: 10.1002/hipo.23215
Abstract: Hippocampal circuitry has been posited to be fundamental to positive symptoms in psychosis, but its contributions to other factors important for outcome remains unclear. We hypothesized that longitudinal changes in the hippocampal circuit and concomitant… read more here.
Keywords: first episode; dynamic anatomical; intracortical microstructure; episode psychosis ... See more keywords
The Horyzons project: a randomized controlled trial of a novel online social therapy to maintain treatment effects from specialist first‐episode psychosis services
Sign Up to like & getrecommendations! Published in 2021 at "World Psychiatry"
DOI: 10.1002/wps.20858
Abstract: This study aimed to determine whether, following two years of specialized support for first‐episode psychosis, the addition of a new digital intervention (Horyzons) to treatment as usual (TAU) for 18 months was more effective than… read more here.
Keywords: randomized controlled; group; first episode; controlled trial ... See more keywords
Early predictors for late hospitalizations up to 14 years after first episode psychosis
Sign Up to like & getrecommendations! Published in 2020 at "Social Psychiatry and Psychiatric Epidemiology"
DOI: 10.1007/s00127-020-01991-w
Abstract: New hospitalizations after first episode psychosis (FEP) may be viewed as an indicator of instability in a psychotic disorder. In the current study we wanted to analyse long term risk for psychosis hospitalizations after FEP.… read more here.
Keywords: first episode; new hospitalizations; psychosis; episode psychosis ... See more keywords
Lessons Learned in Clinical Research Recruitment of Immigrants and Minority Group Members with First-Episode Psychosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Immigrant and Minority Health"
DOI: 10.1007/s10903-018-0704-y
Abstract: Recruitment of immigrants and racial and ethnic minorities with first-episode psychosis (FEP) for research studies presents numerous challenges. We describe methods used to recruit 43 U.S. Latinos with FEP and their family caregivers (n = 41) participating… read more here.
Keywords: recruitment immigrants; research; first episode; episode psychosis ... See more keywords
In Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time–Averaged Proton Magnetic Resonance Spectroscopy at 4T
Sign Up to like & getrecommendations! Published in 2018 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2017.08.022
Abstract: BACKGROUND Accumulating evidence suggests the involvement of abnormal glutamateric neurotransmission and N-methyl-D-aspartate receptor hypofunction in the pathophysiology of psychotic disorders. The purpose of this study was to quantify in vivo glutamate (Glu) and glycine (Gly) levels… read more here.
Keywords: first episode; patients first; spectroscopy; episode psychosis ... See more keywords
Consequences of persistent depression and apathy in first-episode psychosis - A one-year follow-up study.
Sign Up to like & getrecommendations! Published in 2018 at "Comprehensive psychiatry"
DOI: 10.1016/j.comppsych.2018.07.015
Abstract: BACKGROUND Apathy and depression are prevalent in first-episode psychosis (FEP), have overlapping clinical features and are linked to social dysfunction, with indications that persisting symptoms have an even more negative impact. Our objective was to… read more here.
Keywords: depression; one year; first episode; year follow ... See more keywords
SU82 RNA SIGNATURE OF TREATMENT RESPONSE IN FIRST-EPISODE PSYCHOSIS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.271
Abstract: Background Despite nearly fifty years of pharmacological research, the treatment of schizophrenia remains a challenge and clinical outcomes are still far from optimal. One of the major shortcomings in the current treatment of schizophrenia is… read more here.
Keywords: treatment response; response; treatment; first episode ... See more keywords
M96 GENOME-WIDE DNA METHYLATION ANALYSIS IN A LONGITUDINAL COHORT OF ANTIPSYCHOTIC-NAIVE FIRST EPISODE OF PSYCHOSIS PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.403
Abstract: Background The study of the early stages of schizophrenia, the First-Episode Psychosis (FEP), is critical given that brain abnormalities and cognitive deficits are already present. Although less investigated than chronic schizophrenia, FEP individuals have a… read more here.
Keywords: first episode; cohort; antipsychotic naive; dna methylation ... See more keywords
Metabolic syndrome or glucose challenge in first episode of psychosis?
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2016.10.001
Abstract: Abstract Patients with schizophrenia exhibit a reduced life expectancy. Although unhealthy lifestyle or suicide risk plays a role, the main causes are diverse medical conditions such as cardiovascular diseases, type 2 diabetes mellitus and metabolic… read more here.
Keywords: first episode; syndrome glucose; metabolic syndrome; syndrome ... See more keywords
On the Interconnectedness and Prognostic Value of Visual and Auditory Hallucinations in First-Episode Psychosis
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2016.10.011
Abstract: Abstract Background Visual hallucinations (VH) are common symptoms in schizophrenia and other psychoses. An understanding of their cross-sectional and longitudinal patterns of association with auditory hallucinations (AH) is essential for developing accurate models of hallucinatory… read more here.
Keywords: auditory; auditory hallucinations; first episode; interconnectedness prognostic ... See more keywords