Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2
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DOI: 10.1038/s41421-024-00752-2
Abstract: The recent emergence of SARS-CoV-2 variants KP.2 and KP.3 has been marked by mutations F456L/R346T and F456L/Q493E, respectively, which significantly impact the virus’s interaction with human ACE2 and its resistance to neutralizing antibodies. KP.3, featuring… read more here.
Keywords: sars cov; basis epistasis; epistasis effect; structural molecular ... See more keywords