LAUSR

Epistatic Net allows the sparse spectral regularization of deep neural networks for inferring fitness functions

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1 Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-25371-3

Abstract: Despite recent advances in high-throughput combinatorial mutagenesis assays, the number of labeled sequences available to predict molecular functions has remained small for the vastness of the sequence space combined with the ruggedness of many fitness… read more here.

Keywords: fitness functions; deep neural; neural networks; epistatic net ... See more keywords