HDAC6 inhibition and deletion reduce COPD symptoms in mice and human airway epithelia
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DOI: 10.1183/13993003.congress-2020.5033
Abstract: The Histone Deacetylase 6 (HDAC6) enzyme has two deacetylase domains and is found almost exclusively in the cytoplasm. It deacetylates targets such as tubulin, cortactin, HSP90, KU70 and potentially the Treg-specific transcription factor FOXP3 but… read more here.
Keywords: hdac6 inhibition; mice human; epithelia; copd ... See more keywords