Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition
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DOI: 10.1016/j.canlet.2019.08.011
Abstract: The Epidermal Growth Factor Receptor (EGFR) and the Transforming Growth Factor-beta (TGF-β) are key regulators of hepatocarcinogenesis. Targeting EGFR was proposed as a promising therapy; however, poor success was obtained in human hepatocellular carcinoma (HCC)… read more here.
Keywords: egfr; amoeboid transition; epithelial amoeboid; growth factor ... See more keywords