Flat epithelial atypia: are we being too aggressive?
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05481-9
Abstract: Purpose The malignant upgrade rate of flat epithelial atypia (FEA) diagnosed on core needle biopsy varies between 0 and 30%. Excision versus observation with radiological follow-up for these lesions remains controversial. We hypothesize that the… read more here.
Keywords: biopsy; malignant upgrade; pathology; flat epithelial ... See more keywords
Absence of epithelial atypia in B3-lesions of the breast is associated with decreased risk for malignancy.
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DOI: 10.1016/j.breast.2016.11.007
Abstract: INTRODUCTION Lesions of uncertain malignant potential (B3) represent a heterogeneous group with an overall risk for malignancy of 9.85-35.1% after total resection. Positive predictive values (PPV) for malignancy vary depending on B3 subtype. The aim… read more here.
Keywords: ppv; atypia; malignancy; risk malignancy ... See more keywords
Majority of flat epithelial atypia diagnosed on biopsy do not require surgical excision.
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DOI: 10.1016/j.breast.2017.10.005
Abstract: BACKGROUND Borderline risk lesions such as flat epithelial atypia (FEA) are increasingly being diagnosed on biopsy. The need for surgery is being debated. In this study, we determined the frequency of histological upgrade following a… read more here.
Keywords: biopsy; pathology; radiology; flat epithelial ... See more keywords
Flat Epithelial Atypia: Upgrade Rates and Risk-Stratification Approach to Support Informed Decision Making.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2017.08.022
Abstract: BACKGROUND Our aim was to determine upgrade rates of pure flat epithelial atypia (FEA) to malignancy and higher-risk lesions and to identify patients with FEA at low risk for upgrade. STUDY DESIGN Medical chart review… read more here.
Keywords: risk; flat epithelial; malignancy; upgrade rates ... See more keywords