N‐(3‐oxododecanoyl)‐l‐homoserine lactone disrupts intestinal epithelial barrier through triggering apoptosis and collapsing extracellular matrix and tight junction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30261
Abstract: Microbes employ autoinducers of quorum sensing (QS) for population communication. Although the autoinducer of Pseudomonas aeruginosa LasI‐LasR system, N‐(3‐oxododecanoyl)‐ l‐homoserine lactone (3OC12), has been reported with deleterious effects on host cells, its biological effects on… read more here.
Keywords: intestinal epithelial; 3oc12 3oc14; apoptosis; epithelial barrier ... See more keywords
Paeoniflorin‐6′‐O‐benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β‐arrestin 2 on ERK1/2‐NF‐κB
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7657
Abstract: Peoniflorin‐6′‐O‐benzene sulfonate (CP‐25) inhibited the activity of GRK2 to exert anti‐inflammatory and immunomodulatory effects. This study aimed to investigate the effect of CP‐25 the intestinal epithelial barrier and the mechanism. CaCO‐2 cell monolayer and dextran… read more here.
Keywords: epithelial barrier; barrier; grk2 arrestin; intestinal epithelial ... See more keywords
Exploiting the Gastric Epithelial Barrier: Helicobacter pylori's Attack on Tight and Adherens Junctions.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/978-3-319-50520-6_9
Abstract: Highly organized intercellular tight and adherens junctions are crucial structural components for establishing and maintenance of epithelial barrier functions, which control the microbiota and protect against intruding pathogens in humans. Alterations in these complexes represent… read more here.
Keywords: gastric epithelial; adherens junctions; tight adherens; epithelial barrier ... See more keywords
Ion transport mechanisms for smoke inhalation–injured airway epithelial barrier
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology and Toxicology"
DOI: 10.1007/s10565-020-09545-1
Abstract: Smoke inhalation injury is the leading cause of death in firefighters and victims. Inhaled hot air and toxic smoke are the predominant hazards to the respiratory epithelium. We aimed to analyze the effects of thermal… read more here.
Keywords: thermal stress; smoke inhalation; airway epithelial; stress ... See more keywords
Correlation of Probe-Based Confocal Laser Endomicroscopy (pCLE) and Mucosal Integrity Testing (MIT) with Epithelial Barrier Function and Presence of Gastroesophageal Reflux Disease (GERD)
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-06980-w
Abstract: Epithelial barrier function (EBF) disruption is a key mechanism underlying gastroesophageal reflux disease (GERD). Our aim was to assess whether two novel technologies, probe-based confocal laser endomicroscopy (pCLE) and mucosal integrity testing (MIT), could assess… read more here.
Keywords: epithelial barrier; gerd; pcle; mit ... See more keywords
MiR-34c and PlncRNA1 mediated the function of intestinal epithelial barrier by regulating tight junction proteins in inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.115
Abstract: BACKGROUND Inflammatory bowel disease (IBD) is originated from uncontrolled inflammation, and desired methods for IBD therapy remains the main difficult. The network comprised with miRNA and lncRNA has been verified to play an important role… read more here.
Keywords: intestinal epithelial; barrier; function intestinal; plncrna1 ... See more keywords
FABP4 induces asthmatic airway epithelial barrier dysfunction via ROS-activated FoxM1.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.11.106
Abstract: Functional abnormal airway epithelial cells, along with activated inflammatory cells, resulting in chronic airway inflammation, are considered as the characteristic of asthma. Fatty Acid Binding Protein 4 (FABP4) takes part in glucose and lipid homeostasis,… read more here.
Keywords: barrier; barrier dysfunction; airway inflammation; airway epithelial ... See more keywords
1,25-Dihydroxyvitamin D3 targeting VEGF pathway alleviates house dust mite (HDM)-induced airway epithelial barrier dysfunction.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2016.11.004
Abstract: BACKGROUND In our previous studies, we have indentified that 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) can alleviate toluene diisocyanate-induced airway epithelial barrier disruption and we also found that vascular endothelial growth factor (VEGF) derived from airway epithelials cells… read more here.
Keywords: barrier; barrier dysfunction; airway epithelial; induced airway ... See more keywords
Fish-derived low molecular weight components modify bronchial epithelial barrier properties and release of pro-inflammatory cytokines
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.04.029
Abstract: The prevalence of fish allergy among fish-processing workers is higher than in the general population, possibly due to sensitization via inhalation and higher exposure. However, the response of the bronchial epithelium to fish allergens has… read more here.
Keywords: low molecular; barrier; cartilaginous fish; bronchial epithelial ... See more keywords
Pterostilbene Ameliorates DSS-Induced Intestinal Epithelial Barrier Loss in Mice via Suppression of the NF-κB-Mediated MLCK-MLC Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c00274
Abstract: The integrity of the intestinal barrier is critical for homeostasis. In this study, we investigated the protective effect of pterostilbene (PTE) on the intestinal epithelium barrier. In vitro results of transepithelial electrical resistance (TEER) in… read more here.
Keywords: intestinal epithelial; barrier; pterostilbene ameliorates; mlck mlc ... See more keywords
Fucoxanthin Prevents the Ovalbumin-Induced Food Allergic Response by Enhancing the Intestinal Epithelial Barrier and Regulating the Intestinal Flora.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04685
Abstract: This study aimed to determine whether fucoxanthin alleviated ovalbumin (OVA)-induced food allergy (FA) and explored the possible mechanisms. The results indicated that supplementation with fucoxanthin at 10.0-20.0 mg/kg per day for 7 weeks inhibited food… read more here.
Keywords: induced food; intestinal flora; food; epithelial barrier ... See more keywords