Gelatin‐Based Ingestible Impedance Sensor to Evaluate Gastrointestinal Epithelial Barriers
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202211581
Abstract: Low‐profile and transient ingestible electronic capsules for diagnostics and therapeutics can replace widely used yet invasive procedures such as endoscopies. Several gastrointestinal diseases such as reflux disease, Crohn's disease, irritable bowel syndrome, and eosinophilic esophagitis… read more here.
Keywords: gelatin based; epithelial barriers; ingestible impedance; impedance sensor ... See more keywords
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.03.001
Abstract: Autosomal recessive mutations in Inducible T Cell Costimulator Ligand (ICOSLG) result in a combined immunodeficiency syndrome of humans, saliently marked by recurrent respiratory tract infections and significant disease with DNA-based viruses at epithelial barriers, including… read more here.
Keywords: icosl host; icosl icos; host defense; epithelial barriers ... See more keywords
Actin cytoskeleton dynamics during mucosal inflammation: a view from broken epithelial barriers.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in physiology"
DOI: 10.1016/j.cophys.2020.06.012
Abstract: Disruption of epithelial barriers is a key pathogenic event of mucosal inflammation: It ignites the exaggerated immune response and accelerates tissue damage. Loss of barrier function is attributed to the abnormal structure and permeability of… read more here.
Keywords: actin cytoskeleton; disruption; mucosal inflammation; epithelial barriers ... See more keywords
The anuran skin peptide bradykinin mediates its own absorption across epithelial barriers of the digestive tract
Sign Up to like & getrecommendations! Published in 2018 at "Peptides"
DOI: 10.1016/j.peptides.2018.03.010
Abstract: HighlightsSkin secreted bradykinin by frogs does not require absorption enhancing peptides for its uptake across epithelial barriers of the gut.Bradykinin increases the permeability of two cell models of the digestive tract at biologically relevant concentrations.This… read more here.
Keywords: absorption; peptide; across epithelial; epithelial barriers ... See more keywords
Biomimetic Viruslike and Charge Reversible Nanoparticles to Sequentially Overcome Mucus and Epithelial Barriers for Oral Insulin Delivery.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b16524
Abstract: Nanoparticles (NPs) for oral delivery of peptide/protein drugs are largely limited due to the coexistence of intestinal mucus and epithelial barriers. Sequentially overcoming these two barriers is intractable for a single nanovehicle due to the… read more here.
Keywords: nps; delivery; charge; mucus ... See more keywords
Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Tissue Barriers"
DOI: 10.1080/21688370.2017.1356901
Abstract: ABSTRACT The intestinal epithelial cells line the luminal surface of the entire gastrointestinal tract which is crucial for the absorption of nutrients and prevention of pathogens entering from the external environment. The epithelial barrier plays… read more here.
Keywords: inflammatory bowel; neonatal necrotizing; disease; necrotizing enterocolitis ... See more keywords