Targeting of ΔNp63α by miR‐522 promotes the migration of breast epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13072
Abstract: The TP63 gene, which encodes the p63 protein, is involved in multiple biological processes, including embryonic development and tumorigenesis. ΔNp63α, the predominant isoform of p63 in epithelial cells, acts as an oncogene in early‐stage tumors,… read more here.
Keywords: epithelial cells; breast epithelial; mir; targeting np63 ... See more keywords
Fully Biocompatible Tantalum-Based Antioxidant Nanoshields for Proximal Tubule Epithelial Cells-Targeted Mitochondrial Holistic Protection in Acute Kidney Injury.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202506307
Abstract: Acute kidney injury (AKI) has an alarmingly high annual incidence. Heterogeneous AKI shares a common pathological hallmark-excessive reactive oxygen species (ROS), primarily generated from damaged proximal tubular epithelial cells (PTECs). Toxic ROS overload triggers mitochondrial… read more here.
Keywords: tantalum based; biocompatible tantalum; kidney injury; fully biocompatible ... See more keywords
Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis
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DOI: 10.1002/advs.202409756
Abstract: Mitochondrial dysfunction is a key event driving the maladaptive repair of tubular epithelial cells during the transition from acute kidney injury to chronic kidney disease (CKD). Therefore, identifying potential targets involved in mitochondrial dysfunction in… read more here.
Keywords: kidney; mydgf; mitochondrial homeostasis; tubular epithelial ... See more keywords
Scale‐Up of Human Amniotic Epithelial Cells Through Regulation of Epithelial‐Mesenchymal Plasticity Under Defined Conditions (Adv. Sci. 11/2025)
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DOI: 10.1002/advs.202570071
Abstract: Human Amniotic Epithelial Cells Human amniotic epithelial cells (hAECs) originate from the amniotic ectoderm. The proliferation of hAECs during the embryonic development is related to their epithelial mesenchymal plasticity (EMP) properties, which is lost in… read more here.
Keywords: mesenchymal plasticity; amniotic epithelial; epithelial mesenchymal; human amniotic ... See more keywords
AIRE illuminates the feature of medullary thymic epithelial cells in thymic carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5777
Abstract: Despite the clear distinction between cortical (cTECs) and medullary thymic epithelial cells (mTECs) in physiology, the cell of origin of thymic carcinomas (TCs) and other thymic epithelial tumors remained enigmatic. We addressed this issue by… read more here.
Keywords: thymic epithelial; tcs; aire illuminates; epithelial cells ... See more keywords
Aqueous Rosa damascena extract: Antibacterial activity and its role of adhesion to human epithelial cells in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3788
Abstract: The current study aimed to investigate the inhibitory activity of aqueous extracts of different plant parts of Rosa damascena, represented by the whole rose, petals, and calyces, against clinical isolates of Staphylococcus spp., Escherichia coli,… read more here.
Keywords: rosa damascena; staphylococcus; activity; plant ... See more keywords
IL‐1β functionally attenuates ABCG2 and PDZK1 expression in HK‐2 cells partially through NF‐ĸB activation
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DOI: 10.1002/cbin.11100
Abstract: Long‐standing untreated hyperuricemia could lead to gout. Several recent studies have demonstrated a significant decrease of serum urate during acute gout attack, which is an aseptic inflammation process focusing on IL‐1β. However, how IL‐1β, by… read more here.
Keywords: epithelial cells; attenuates abcg2; renal tubular; expression ... See more keywords
Strategies for immortalisation of amnion‐derived mesenchymal and epithelial cells
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DOI: 10.1002/cbin.11892
Abstract: Mesenchymal (human amniotic mesenchymal stem cell [HAMSC]) and epithelial cells (human amnion epithelial cell [HAEC]) derived from human amniotic membranes possess characteristics of pluripotency. However, the pluripotency of HAMSC and HAEC are sustained only for… read more here.
Keywords: cell; strategies immortalisation; amnion; amnion derived ... See more keywords
Prolactin regulates RANKL expression via signal transducer and activator of transcription 5a signaling in mammary epithelial cells of dairy cows
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11988
Abstract: Receptor of activated nuclear factor kappa B ligand (RANKL) is regulated by prolactin in the mammary gland. However, the intrinsic molecular mechanism is not well understood. Herein, mammary epithelial cells (MECs) of dairy cows were… read more here.
Keywords: expression; rankl; epithelial cells; prolactin ... See more keywords
Synthesis of Unsymmetrical Squaramides as Allosteric GSK‐3β Inhibitors Promoting β‐Catenin‐Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200456
Abstract: The glycogen synthase kinase 3β (GSK‐3β) is a ubiquitous enzyme that is a validated target for the development of potential therapeutics useful in several diseases including retinal degeneration. Aiming at developing an innovative class of… read more here.
Keywords: epithelial cells; pigment epithelial; retinal pigment; tcf lef ... See more keywords
Contribution of the coelomic epithelial cells specific to the left testis in the chicken embryo
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DOI: 10.1002/dvdy.24469
Abstract: Background: The left male gonad in the chicken embryo has a thickened cortical layer, but it eventually becomes flattened after the onset of testicular development. Because the destination of the cortical cells migrating from the… read more here.
Keywords: testis; epithelial cells; chicken embryo; left testis ... See more keywords