Intestinal epithelial damage due to herbal compounds – an in vitro study
Sign Up to like & getrecommendations! Published in 2022 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2021.2021929
Abstract: Abstract Intestinal epithelial injury from herbal products has rarely been reported, despite the gut being the first point of contact for oral preparations. These products often consist of multiple herbs, thereby potentially exposing consumers to… read more here.
Keywords: toxicity; damage due; coumarin; epithelial damage ... See more keywords
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1101/2022.03.15.484379
Abstract: Understanding the host pathways that define susceptibility to SARS-CoV-2 infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcriptional landscape, however the influence of hypoxia on… read more here.
Keywords: respiratory symptoms; epithelial damage; respiratory; damage respiratory ... See more keywords
Irrigating the eye after intravitreal injection reduces epithelial damage but not patient discomfort
Sign Up to like & getrecommendations! Published in 2019 at "Acta Ophthalmologica"
DOI: 10.1111/aos.14014
Abstract: Fishman GA, Stone EM, Gilbert LD & Sheffield VC (1992): Ocular findings associated with a rhodopsin gene codon 106 mutation. Glycine-to-arginine change in autosomal dominant retinitis pigmentosa. Arch Ophthalmol 110: 646–653. Fledelius HC & Rosenberg… read more here.
Keywords: intravitreal injection; reduces epithelial; injection reduces; eye intravitreal ... See more keywords
Effects of nintedanib on markers of epithelial damage in subjects with IPF: data from the INMARK trial
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DOI: 10.1183/13993003.congress-2020.5187
Abstract: Introduction: The INMARK trial investigated effects of nintedanib on blood biomarkers in subjects with IPF. Aim: To investigate the effect of nintedanib on markers of epithelial damage. Methods: Subjects (n=346) with IPF and FVC ≥80%… read more here.
Keywords: markers epithelial; effects nintedanib; subjects ipf; epithelial damage ... See more keywords
Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection
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DOI: 10.1371/journal.ppat.1010323
Abstract: Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea and pseudomembranous colitis in the USA. In addition to these symptoms, patients with CDI can develop severe inflammation and tissue damage, resulting in life-threatening… read more here.
Keywords: clostridioides difficile; difficile toxins; cdi; epithelial damage ... See more keywords
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of veterinary research"
DOI: 10.2460/ajvr.81.2.139
Abstract: OBJECTIVE To evaluate the usefulness of intestinal biomarkers in determining the presence of intestinal epithelial damage in neonatal calves with diarrhea caused by 4 etiologic agents. ANIMALS 40 neonatal calves that were healthy (n =… read more here.
Keywords: intestinal epithelial; serum concentrations; neonatal calves; epithelial damage ... See more keywords
Distinct Cohorts of Aspergillus fumigatus Transcription Factors Are Required for Epithelial Damage Occurring via Contact- or Soluble Effector-Mediated Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.907519
Abstract: Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic fungus Aspergillus fumigatus. However, the mechanistic basis and the regulatory control of such damage is poorly characterized. Previous studies have… read more here.
Keywords: damage; transcription; aspergillus fumigatus; early late ... See more keywords
Melatonin Type 2 Receptor Activation Regulates Blue Light Exposure-Induced Mouse Corneal Epithelial Damage by Modulating Impaired Autophagy and Apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911341
Abstract: The MT1/2 receptors, members of the melatonin receptor, belong to G protein-coupled receptors and mainly regulate circadian rhythms and sleep in the brain. Previous studies have shown that in many other cells and tissues, such… read more here.
Keywords: apoptosis; damage; corneal epithelial; expression ... See more keywords
COVID-19: Extensive epithelial damage and ciliary dyskinesia in hospitalised patients.
Sign Up to like & getrecommendations! Published in 2022 at "Rhinology"
DOI: 10.4193/rhin21.233
Abstract: Infection with SARS-CoV-2 can cause severe respiratory disease and it is predicted that the COVID-19 pandemic will leave a substantial number of patients with long-term respiratory complications (1). read more here.
Keywords: epithelial damage; extensive epithelial; damage ciliary; ciliary dyskinesia ... See more keywords