LAUSR

Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation

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3 Published in 2023 at "JCI Insight"

DOI: 10.1172/jci.insight.162701

Abstract: As a hallmark of inflammatory bowel disease (IBD), elevated intestinal epithelial cell (IEC) death compromises the gut barrier, activating the inflammatory response and triggering more IEC death. However, the precise intracellular machinery that prevents IEC… read more here.

Keywords: necroptosis; ripk3 dependent; gab1; epithelial gab1 ... See more keywords