Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101026
Abstract: Highlights • No unique genome signature or molecular therapy exists for inflammatory breast cancer (IBC), a highly aggressive breast cancer with a 5-year survival rate of less than 30%.• We show that various gene lists… read more here.
Keywords: hybrid mesenchymal; epithelial hybrid; mesenchymal spectrum; breast cancer ... See more keywords
Quantifying the Patterns of Metabolic Plasticity and Heterogeneity along the Epithelial–Hybrid–Mesenchymal Spectrum in Cancer
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DOI: 10.3390/biom12020297
Abstract: Cancer metastasis is the leading cause of cancer-related mortality and the process of the epithelial-to-mesenchymal transition (EMT) is crucial for cancer metastasis. Both partial and complete EMT have been reported to influence the metabolic plasticity… read more here.
Keywords: epithelial hybrid; metabolic plasticity; plasticity heterogeneity; patterns metabolic ... See more keywords