MiR‐3175 promotes epithelial‐mesenchymal transition by targeting Smad7 in human conjunctiva and pterygium
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13698
Abstract: MicroRNAs (miRNAs) are involved in the post‐transcriptional regulation of mRNAs. However, the function of miRNAs is unclear in epithelial–mesenchymal transition (EMT) of pterygium, a disease characterized by abnormal fibrovascular proliferation and invasion on the ocular… read more here.
Keywords: mesenchymal transition; 3175 promotes; pterygium; epithelial mesenchymal ... See more keywords
A 17 gene panel for non‐small‐cell lung cancer prognosis identified through integrative epigenomic‐transcriptomic analyses of hypoxia‐induced epithelial–mesenchymal transition
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12491
Abstract: As a critical feature of the tumor microenvironment, hypoxia is known to be a potent inducer of tumor metastasis, and it has been proposed that the initial steps in metastasis involve epithelial–mesenchymal transition (EMT). The… read more here.
Keywords: mesenchymal transition; epithelial mesenchymal; non small; gene ... See more keywords
The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial‐to‐mesenchymal transition and lipid‐derived energy production in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12818
Abstract: Early stage localized prostate cancer (PCa) has an excellent prognosis; however, patient survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying PCa metastasis are complex and remain unclear. Here, we examine the role of… read more here.
Keywords: mesenchymal transition; production; energy production; prostate cancer ... See more keywords
TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular oncology"
DOI: 10.1002/1878-0261.13215
Abstract: Transforming growth factor β (TGFβ) induces epithelial-mesenchymal transition (EMT), which correlates with stemness and invasiveness. Mesenchymal-epithelial transition (MET) is induced by TGFβ withdrawal and correlates with metastatic colonization. Whether TGFβ promotes stemness and invasiveness simultaneously… read more here.
Keywords: mesenchymal transition; cancer cell; tgf; pro stemness ... See more keywords
Carbon Dots Induce Epithelial‐Mesenchymal Transition for Promoting Cutaneous Wound Healing via Activation of TGF‐β/p38/Snail Pathway
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DOI: 10.1002/adfm.202004886
Abstract: Skin lesions, as a relatively common clinical manifestation, not only damage the skin's barrier function, but also affect the skin's ability to feel temperature, pain and touch. However, a highly efficient method to restore the… read more here.
Keywords: mesenchymal transition; induce epithelial; wound healing; carbon dots ... See more keywords
METTL3 Mediates Epithelial-Mesenchymal Transition by Modulating FOXO1 mRNA N6 -Methyladenosine-Dependent YTHDF2 Binding: A Novel Mechanism of Radiation-Induced Lung Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202204784
Abstract: The biological roles of epithelial-mesenchymal transition (EMT) in the pathogenesis of radiation-induced lung injury (RILI) have been widely demonstrated, but the mechanisms involved have been incompletely elucidated. N6 -methyladenosine (m6 A) modification, the most abundant… read more here.
Keywords: ythdf2; modification; epithelial mesenchymal; radiation induced ... See more keywords
Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial‐mesenchymal transition via Hedgehog signaling pathway
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DOI: 10.1002/cam4.1752
Abstract: Based on previous findings, we hypothesized that Vasohibin 2 (VASH2) protein may induce epithelial‐mesenchymal transition (EMT) of pancreatic cancer (PC) cells by promoting the malignant behaviors of these cells. The present study aimed to test… read more here.
Keywords: malignant behaviors; mesenchymal transition; pancreatic cancer; epithelial mesenchymal ... See more keywords
Resveratrol promotes sensitization to Doxorubicin by inhibiting epithelial‐mesenchymal transition and modulating SIRT1/β‐catenin signaling pathway in breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1993
Abstract: Breast cancer is one of the leading fatal diseases for women worldwide who cannot have surgery typically have to rely on systemic chemotherapy to extend their survival. Doxorubicin (DOX) is one of the most commonly… read more here.
Keywords: sirt1 catenin; breast cancer; epithelial mesenchymal; doxorubicin ... See more keywords
Long non‐coding RNA HULC stimulates the epithelial–mesenchymal transition process and vasculogenic mimicry in human glioblastoma
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DOI: 10.1002/cam4.4083
Abstract: Long non‐coding RNA (lncRNA) HULC (highly upregulated in liver cancer) is considered as an oncogenic factor for various malignant tumors. This study aimed to reveal the role of lncRNA HULC in the malignant behavior of… read more here.
Keywords: mesenchymal transition; hulc; long non; non coding ... See more keywords
Identification of a novel prognostic signature correlated with epithelial‐mesenchymal transition, N6‐methyladenosine modification, and immune infiltration in colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5384
Abstract: Colorectal cancer (CRC) is a commonly diagnosed human malignancy worldwide. Both epithelial‐mesenchymal transition (EMT) and N6‐methyladenosine (m6A) modification play a crucial role in CRC development. This study aimed to construct a prognostic signature based on… read more here.
Keywords: modification; mesenchymal transition; prognostic signature; colorectal cancer ... See more keywords
ESE1/AGR2 axis antagonizes TGF‐β‐induced epithelial‐mesenchymal transition in low‐grade pancreatic cancer
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DOI: 10.1002/cam4.5397
Abstract: Epithelium‐specific ETS transcription factor 1 (ESE1) has been implicated in epithelial homeostasis, inflammation, as well as tumorigenesis, and cancer progression. However, numerous studies have reported contradictory roles—as an oncogene or a tumor suppressor of ESE1… read more here.
Keywords: mesenchymal transition; tgf induced; ese1; epithelial mesenchymal ... See more keywords