Epithelial monitoring through ligand-receptor segregation ensures malignant cell elimination
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DOI: 10.1126/science.abl4213
Abstract: Animals have evolved mechanisms, such as cell competition, to remove dangerous or nonfunctional cells from a tissue. Tumor necrosis factor signaling can eliminate clonal malignancies from Drosophila imaginal epithelia, but why this pathway is activated… read more here.
Keywords: cell; ligand receptor; epithelial monitoring; ligand ... See more keywords