Transmigration of Leukocytes Across Epithelial Monolayers.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7701-7_7
Abstract: Migration of leukocytes through epithelial monolayers represents an essential step in the generation of an inflammatory response and is often seen in inflammatory conditions such as Crohn's disease (Matthews et al., Toxicol Pathol 42:91-98, 2014)… read more here.
Keywords: leukocytes across; across epithelial; epithelial monolayers; migration ... See more keywords
Force Localization and Cell Shape in Epithelial Monolayers
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2323
Abstract: Epithelial monolayers are a classic system of active matter, in which the component particles (cells) endogenously generate forces and change their own shapes without external stimuli. The mechanics of single cells and circular colonies of… read more here.
Keywords: localization cell; epithelial monolayers; cell shape; force localization ... See more keywords
Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2019.06.012
Abstract: Vitamin A (VA) is a fat-soluble micronutrient that plays essential roles in various biological processes, including cell growth, differentiation, and apoptosis. In the intestine, VA are known to promote mucosal homeostasis and immunity. However, the… read more here.
Keywords: intestinal epithelial; derived intestinal; promotes barrier; epithelial monolayers ... See more keywords
P111 Dietary emulsifier κ-carrageenan does not directly affect intestinal permeability in organoid-derived epithelial monolayers from patients with Crohn’s disease
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.0241
Abstract: The dietary emulsifier carrageenan (CGN) is widely used to optimise the texture of processed foods such as ice cream, plant-based milk and processed meat products. However, CGN is suggested to play a role in IBD… read more here.
Keywords: organoid derived; permeability; dietary emulsifier; culture ... See more keywords
Variable disruption of epithelial monolayers by Neisseria meningitidis carriage isolates of the hypervirulent MenW cc11 and MenY cc23 lineages
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology"
DOI: 10.1099/mic.0.001305
Abstract: Colonization of mucosal tissues by Neisseria meningitidis requires adhesion mediated by the type IV pilus and multiple outer-membrane proteins. Penetration of the mucosa and invasion of epithelial cells are thought to contribute to host persistence… read more here.
Keywords: adhesion; cc11; disruption; carriage isolates ... See more keywords
Unbuckling Mechanics of Epithelial Monolayers under Compression.
Sign Up to like & getrecommendations! Published in 2024 at "Physical review letters"
DOI: 10.1103/physrevlett.134.118402
Abstract: When cell sheets fold during development, their apical or basal surfaces constrict and cell shapes approach the geometric singularity in which these surfaces vanish. Here, we reveal the mechanical consequences of this geometric singularity for… read more here.
Keywords: mechanics epithelial; mechanics; epithelial monolayers; compression ... See more keywords
E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding.
Sign Up to like & getrecommendations! Published in 2025 at "Science signaling"
DOI: 10.1126/scisignal.adr7926
Abstract: The behavior of cells is governed by signals originating from their local environment, including mechanical forces exerted on the cells. Forces are transduced by mechanosensitive proteins, which can impinge on signaling cascades that are also… read more here.
Keywords: erk signaling; epithelial monolayers; adam mediated; egfr erk ... See more keywords
Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9040490
Abstract: Aspergillus fumigatus is the most commonly isolated fungus in chronic lung diseases, with a prevalence of up to 60% in cystic fibrosis patients. Despite this, the impact of A. fumigatus colonisation on lung epithelia has… read more here.
Keywords: bronchial epithelial; aspergillus fumigatus; fumigatus; fumigatus supernatants ... See more keywords
Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12040632
Abstract: Background: The effect of presently available CFTR modulator combinations, such as elexacaftor (ELX), tezacaftor (TEZ), and ivacaftor (IVA), on rare CFTR alleles is often unknown. Several assays have been developed, such as forskolin-induced swelling (FIS),… read more here.
Keywords: medicine; iva; organoid derived; epithelial monolayers ... See more keywords
Modelling of Tissue Invasion in Epithelial Monolayers
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13020427
Abstract: Mathematical and computational models are used to describe biomechanical processes in multicellular systems. Here, we develop a model to analyse how two types of epithelial cell layers interact during tissue invasion depending on their cellular… read more here.
Keywords: epithelial monolayers; tissue invasion; invasion; modelling tissue ... See more keywords