Exosomal microRNAs as tumor markers in epithelial ovarian cancer
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DOI: 10.1002/1878-0261.12371
Abstract: Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles… read more here.
Keywords: epithelial ovarian; mir; mir 200b; ovarian cancer ... See more keywords
The prognostic effect of residual tumor for advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy or primary debulking surgery
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DOI: 10.1002/cam4.4642
Abstract: The role of neoadjuvant chemotherapy (NACT) and primary debulking surgery (PDS) in advanced epithelial ovarian cancer (EOC) remains controversial. This study aimed to investigate the prognosis between NACT and PDS in advanced EOC. We also… read more here.
Keywords: neoadjuvant chemotherapy; epithelial ovarian; advanced epithelial; primary debulking ... See more keywords
What is the role of retroperitoneal exploration in optimally debulked stage IIIC epithelial ovarian cancer? An NRG Oncology/Gynecologic Oncology Group ancillary data study
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DOI: 10.1002/cncr.30414
Abstract: The purpose of this study was to determine the effect of retroperitoneal (RP) exploration on progression‐free survival (PFS) and overall survival (OS) in epithelial ovarian cancer (EOC) patients with stage IIIC disease who underwent optimal… read more here.
Keywords: epithelial ovarian; ovarian cancer; retroperitoneal exploration; cancer ... See more keywords
Residential segregation and overall survival of women with epithelial ovarian cancer
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DOI: 10.1002/cncr.32989
Abstract: To the authors' knowledge, the etiology of survival disparities in patients with epithelial ovarian cancer (EOC) is not fully understood. Residential segregation, both economic and racial, remains a problem within the United States. The objective… read more here.
Keywords: epithelial ovarian; residential segregation; ovarian cancer; cancer ... See more keywords
Prevalence, spectrum, and founder effect of BRCA1 and BRCA2 mutations in epithelial ovarian cancer from the Middle East
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DOI: 10.1002/humu.23736
Abstract: Germline mutations in breast cancer susceptibility gene 1 and 2 have previously been estimated to contribute to 13–18% of all epithelial ovarian cancer (EOC). To characterize the prevalence and effect of BRCA1 and BRCA2 mutations… read more here.
Keywords: founder; epithelial ovarian; prevalence; effect ... See more keywords
Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer
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DOI: 10.1002/ijc.30860
Abstract: Aim was to identify methylated genes with functional involvement in cisplatin‐resistance development of epithelial ovarian cancer (EOC). Genome‐wide analyses of hypermethylated CpG‐islands in resistant cell lines in combination with qRT‐PCR analyses were used to identify… read more here.
Keywords: epithelial ovarian; cisplatin; expression; ovarian cancer ... See more keywords
Preterm delivery is associated with an increased risk of epithelial ovarian cancer among parous women
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DOI: 10.1002/ijc.31581
Abstract: Epithelial ovarian cancer is a fatal disease of largely unknown etiology. Higher parity is associated with reduced risk of ovarian cancer. However, among parous women, the impact of pregnancy‐related factors on risk is not well… read more here.
Keywords: risk; epithelial ovarian; pregnancy; ovarian cancer ... See more keywords
Selection of small plasma peptides for the auxiliary diagnosis and prognosis of epithelial ovarian cancer by using UPLC/MS‐based nontargeted and targeted analyses
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DOI: 10.1002/ijc.31807
Abstract: Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer‐related death due to its nonspecific characteristics compared to benign cases and poor prognosis after conventional therapies. Small peptides (SPs) demonstrated to have potential for… read more here.
Keywords: epithelial ovarian; diagnosis; ovarian cancer; cancer ... See more keywords
Long noncoding RNA TC0101441 induces epithelial–mesenchymal transition in epithelial ovarian cancer metastasis by downregulating KiSS1
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DOI: 10.1002/ijc.32692
Abstract: Peritoneal metastasis is a critical feature and clinical challenge in epithelial ovarian cancer (EOC). We previously identified a novel long noncoding RNA (lncRNA, TC0101441) in epithelial ovarian cancer (EOC) using microarrays. However, the impact of… read more here.
Keywords: long noncoding; epithelial ovarian; metastasis; ovarian cancer ... See more keywords
A comprehensive investigation of histotype‐specific microRNA and their variants in Stage I epithelial ovarian cancers
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DOI: 10.1002/ijc.34408
Abstract: isomiRs, the sequence‐variants of microRNA, are known to be tissue and cell type specific but their physiological role is largely unknown. In our study, we explored for the first time the expression of isomiRs across… read more here.
Keywords: stage epithelial; epithelial ovarian; investigation histotype; comprehensive investigation ... See more keywords
Safety and efficacy of neoadjuvant chemotherapy containing bevacizumab and interval debulking surgery for advanced epithelial ovarian cancer: A feasibility study
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DOI: 10.1002/jso.25187
Abstract: The optimum treatment strategy for patients with unresectable advanced epithelial ovarian cancer is controversial. This study examined bevacizumab combined with neoadjuvant chemotherapy (NAC; paclitaxel plus carboplatin), followed by interval debulking surgery (IDS), for these patients. read more here.
Keywords: epithelial ovarian; advanced epithelial; ovarian cancer; neoadjuvant chemotherapy ... See more keywords