Epithelial Regnase-1 inhibits colorectal tumor growth by regulating IL-17 signaling via degradation of NFKBIZ mRNA
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DOI: 10.1073/pnas.2500820122
Abstract: Significance Regnase-1, a messenger RNA (mRNA)-degrading enzyme, plays a critical role in regulating inflammation in immune cells. In the current study, its role in intestinal epithelial cells during tumorigenesis has been revealed. Using an original… read more here.
Keywords: epithelial regnase; regnase inhibits; regnase; tumor ... See more keywords