Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41116-1
Abstract: Adhesion signaling between epithelial cells and the extracellular matrix plays a critical role in maintaining tissue homeostasis and the response to tissue damage. Focal adhesion kinase (FAK) and its close relative Pyk2 are non-receptor tyrosine… read more here.
Keywords: non redundant; epithelial repair; redundant functions; colitis ... See more keywords
Targeting NRF2 to promote epithelial repair
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society Transactions"
DOI: 10.1042/bst20220228
Abstract: The transcription factor NRF2 is well known as a master regulator of the cellular stress response. As such, activation of NRF2 has gained widespread attention for its potential to prevent tissue injury, but also as… read more here.
Keywords: nrf2 promote; epithelial repair; promote epithelial; targeting nrf2 ... See more keywords
Pretreatment with bacterial components promotes DSS-injured colonic epithelial repair through the activation of STAT-3.
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DOI: 10.3892/mmr.2017.6812
Abstract: Bacterial protection and epithelial repair are important against inflammatory bowel disease (IBD). The present study was designed to examine the effects of different bacterial components on the repair of normal and dextran sodium sulfate (DSS)‑treated… read more here.
Keywords: epithelial repair; lps cpg; colonic epithelial; activation ... See more keywords