Molecular investigation of ALK‐rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion‐independent transcription activation
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.1002/gcc.23038
Abstract: Epithelioid fibrous histiocytoma (EFH) is a rare cutaneous neoplasm, which is characterized by the presence of rearrangements involving the ALK gene. Although EFH was long considered a variant of fibrous histiocytoma, the identification of its… read more here.
Keywords: fusion partner; fusion; epithelioid fibrous; alk ... See more keywords
Epithelioid fibrous histiocytoma: molecular characterization of ALK fusion partners in 23 cases
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DOI: 10.1038/modpathol.2017.191
Abstract: Epithelioid fibrous histiocytoma is a rare and distinctive cutaneous neoplasm. Most cases harbor ALK rearrangement and show ALK overexpression, which distinguish this neoplasm from conventional cutaneous fibrous histiocytoma and variants. SQSTM1 and VCL have previously… read more here.
Keywords: alk fusion; alk; epithelioid fibrous; fibrous histiocytoma ... See more keywords