Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV
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DOI: 10.1080/19420862.2017.1319023
Abstract: ABSTRACT Human epidermal growth factor receptor 3 (HER3, also known as ErbB3) has emerged as relevant target for antibody-mediated tumor therapy. Here, we describe a novel human antibody, IgG 3–43, recognizing a unique epitope formed… read more here.
Keywords: epitope formed; human antibody; her3; growth ... See more keywords