Non-synonymous mutations of SARS-CoV-2 leads epitope loss and segregates its variants
Sign Up to like & getrecommendations! Published in 2020 at "Microbes and Infection"
DOI: 10.1016/j.micinf.2020.10.004
Abstract: The non-synonymous mutations of SARS-CoV-2 isolated from across the world have been identified during the last few months. The surface glycoprotein spike of SARS-CoV-2 forms the most important hotspot for amino acid alterations followed by… read more here.
Keywords: mutations sars; synonymous mutations; loss; epitope loss ... See more keywords
Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.918928
Abstract: To provide a unique global view of the relative potential for evasion of CD8+ and CD4+ T cells by SARS-CoV-2 lineages as they evolve over time, we performed a comprehensive analysis of predicted HLA-I and… read more here.
Keywords: cell; loss; sars cov; hla binding ... See more keywords