Development of Avian Avulavirus 1 Epitope-Based Vaccine Pattern Based on Epitope Prediction and Molecular Docking Analysis: An Immunoinformatic Approach
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-019-09952-x
Abstract: Fusion (F) and Hemagglutinin-neuraminidase (HN) glycoproteins of Newcastle disease virus containing important epitopes play crucial role in stimulation of humoral and cell-mediated immunity of the host. In the present study we analyzed and compared genetic… read more here.
Keywords: docking analysis; epitope; molecular docking; epitope prediction ... See more keywords
epitope3D: a machine learning method for conformational B-cell epitope prediction.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab423
Abstract: The ability to identify antigenic determinants of pathogens, or epitopes, is fundamental to guide rational vaccine development and immunotherapies, which are particularly relevant for rapid pandemic response. A range of computational tools has been developed… read more here.
Keywords: machine learning; conformational cell; learning method; epitope ... See more keywords
SEPPA-mAb: spatial epitope prediction of protein antigens for mAbs.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad427
Abstract: Identifying the exact epitope positions for a monoclonal antibody (mAb) is of critical importance yet highly challenging to the Ab design of biomedical research. Based on previous versions of SEPPA 3.0, we present SEPPA-mAb for… read more here.
Keywords: seppa mab; epitope prediction; epitope;
BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx346
Abstract: Abstract Antibodies have become an indispensable tool for many biotechnological and clinical applications. They bind their molecular target (antigen) by recognizing a portion of its structure (epitope) in a highly specific manner. The ability to… read more here.
Keywords: cell; sequence based; antigen; epitope ... See more keywords
Comprehending B-Cell Epitope Prediction to Develop Vaccines and Immunodiagnostics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.908459
Abstract: B-cell epitope prediction (BCEP) is the original subject of immunoinformatics (i.e., bioinformatics applied to immunology). This began with protein sequence analysis to identify hydrophilic peptide fragments bound by antibodies that recognize whole proteins (1), to… read more here.
Keywords: cell; epitope prediction; cell epitope; vaccines immunodiagnostics ... See more keywords