Extracellular Hsp90α Supports the ePKM2-GRP78-AKT Axis to Promote Tumor Metastasis
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DOI: 10.3389/fonc.2022.906080
Abstract: Tumor-secreted proteins can provide numerous molecular targets for cancer diagnosis and treatment. Of note, pyruvate kinase M2 (PKM2) is secreted by tumor cells to promote malignant progression, while its regulatory mechanism or the interacting network… read more here.
Keywords: grp78 akt; hsp90; akt axis; epkm2 grp78 ... See more keywords