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   Articles with "epo" as a keyword



Detection of a non-erythropoietic EPO, Neuro-EPO, in blood after intra-nasal administration in rat.

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recommendations! Published in 2020 at "Drug testing and analysis"

DOI: 10.1002/dta.2924

Abstract: Non-erythropoietic erythropoietin (EPO) are investigated for their high anti-oxidant properties. A new drug candidate under clinical investigation to treat brain diseases is Neuro-EPO, produced by selecting EPO isoforms with low sialic acid content. Intra-nasal administration… read more here.

Keywords: administration; detection; neuro epo; epo ... See more keywords

Detection of De-N-Glycosylated EPO with SDS-PAGE: A Complementary Confirmation Procedure for Recombinant EPO in Blood Samples.

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recommendations! Published in 2022 at "Drug testing and analysis"

DOI: 10.1002/dta.3324

Abstract: Frameshift variant c.577del in the EPO gene can result in the extension of the Amino Acid sequence of EPO by invalidating the termination codon. As the molecular weight of its encoded protein EPO (VAR-EPO) is… read more here.

Keywords: epo; complementary confirmation; blood samples; glycosylated epo ... See more keywords

Study on Internal Standards Applicable to the Detection of Recombinant Erythropoietin.

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recommendations! Published in 2024 at "Drug testing and analysis"

DOI: 10.1002/dta.3836

Abstract: With the discovery of the variant c.577del in the EPO gene, the procedure for detecting the presence of recombinant erythropoietin (rEPO) has become complicated and time-consuming. To address this situation, an rEPO confirmation method that… read more here.

Keywords: var epo; epo; recombinant erythropoietin;

Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers

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recommendations! Published in 2025 at "Drug Testing and Analysis"

DOI: 10.1002/dta.3932

Abstract: ABSTRACT Doping with testosterone (T) and erythropoietin (EPO) in low doses (micro‐doping) is a challenge to detect. Here, we have investigated the ability to detect micro‐doping of recombinant human (rhEPO) and testosterone (T) after administration… read more here.

Keywords: detection; detection single; epo; single microdose ... See more keywords
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C‐Terminal, but Not Intact, FGF23 and EPO Are Strongly Correlatively Elevated in Patients With Gain‐of‐Function Mutations in HIF2A: Clinical Evidence for EPO Regulating FGF23

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recommendations! Published in 2020 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4195

Abstract: Fibroblast growth factor 23 (FGF23) is a key phosphate‐ and vitamin D‐regulating hormone. FGF23 circulates as an intact 251 amino acid protein or N‐ and C‐terminal degradation products. Hormone activity resides in the intact molecule,… read more here.

Keywords: fgf23; function mutations; intact fgf23; physiology ... See more keywords
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Comparison of Misoprostol and Evening Primrose on Cervical Preparation Before Gynecological Surgery.

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recommendations! Published in 2023 at "Journal of clinical pharmacology"

DOI: 10.1002/jcph.2253

Abstract: This study aimed to evaluate the efficacy and safety of evening primrose oil(EPO) for cervical ripening before gynecologic procedures and compare it to misoprostol. In this study,40 hysteroscopy, dilation and curettage (D&C) candidates were enrolled.… read more here.

Keywords: epo; evening primrose; misoprostol; group ... See more keywords
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Development of a stable chemically cross-linked erythropoietin dimer for use in the quality control of erythropoietin therapeutic products

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recommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-019-01768-4

Abstract: AbstractErythropoietin (EPO) is a glycoprotein hormone which promotes red cell replenishment and is also a global biotherapeutic medicine widely used to treat anaemia resulting, for example, from chemotherapy. Requirements of the European Pharmacopoeia stipulate that… read more here.

Keywords: chemically cross; stable chemically; cross linked; epo ... See more keywords

Long-term results of a pilot study evaluating hyperbaric oxygen therapy to improve umbilical cord blood engraftment

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recommendations! Published in 2018 at "Annals of Hematology"

DOI: 10.1007/s00277-018-3532-1

Abstract: Umbilical cord blood (UCB) transplantation is a promising option for hematopoietic stem cell transplantation in patients with hematologic malignancies who lack an HLA-matched sibling or well-matched unrelated donor; however, it has a higher incidence of… read more here.

Keywords: hbo; long term; epo; therapy ... See more keywords

An Apparent Correlation Between Central Nervous System and Kidney’s Erythropoietin and TNF Alpha Expression at Peak Experimental Autoimmune Encephalomyelitis Disease

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recommendations! Published in 2018 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-018-1092-4

Abstract: Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelination disease associated with inflammatory reactions and attenuation of antioxidant capacity. Several lines of evidence show that organs such as the liver and kidneys can share their antioxidant… read more here.

Keywords: tnf; epo; expression; autoimmune encephalomyelitis ... See more keywords

Erythropoietin protects neurons from apoptosis via activating PI3K/AKT and inhibiting Erk1/2 signaling pathway

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recommendations! Published in 2019 at "3 Biotech"

DOI: 10.1007/s13205-019-1667-y

Abstract: The aim of this study was to explore the neuroprotective effect and the underlying mechanism of erythropoietin (EPO) on the cortical neuronal cells insulted with oxygen and glucose deprivation (OGD). Different concentrations of EPO were… read more here.

Keywords: akt; apoptosis; effect; erk1 ... See more keywords

Effect of erythropoietin production induced by hypoxia on autophagy in HepG2 cells.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.11.167

Abstract: The induction of hypoxia inducible factor (HIF) and autophagy are important cellular responses to hypoxia. The production of erythropoietin (EPO) regulated by HIF is increased by hypoxia and participates in cell protection in various organs… read more here.

Keywords: production; epo; hypoxia; autophagy induction ... See more keywords