Efficacy and safety of HIF prolyl-hydroxylase inhibitor vs epoetin and darbepoetin for anemia in chronic kidney disease patients not undergoing dialysis: a network meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105020
Abstract: Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of oral medicines being developed for the treatment of anemia in chronic kidney disease (CKD) patients. This study aimed to compare the efficacy and safety… read more here.
Keywords: epoetin darbepoetin; hif; undergoing dialysis; epoetin ... See more keywords
Evaluating the utilisation and expenditure patterns of erythropoietin stimulating agents and immunosuppressants in Australian chronic kidney disease patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Health Services Research"
DOI: 10.1093/jphsr/rmab027
Abstract: This study aimed to characterise utilisation and expenditure patterns associated with erythropoietin stimulating agents (ESAs) (darbepoetin alfa, epoetin alfa, epoetin beta, epoetin lambda and methoxy polyethylene glycol-epoetin beta) and immunosuppressants (mycophenolate, tacrolimus, ciclosporine, sirolimus and… read more here.
Keywords: expenditure patterns; utilisation; erythropoietin stimulating; expenditure ... See more keywords
Roxadustat Versus Epoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis: Results from the Randomized Phase 3 ROCKIES Study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2020111638
Abstract: BACKGROUND Concerns regarding cardiovascular safety with current treatments for anemia in patients with dialysis-dependent (DD)-CKD have encouraged the development of alternatives. Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, stimulates erythropoiesis by increasing endogenous erythropoietin… read more here.
Keywords: epoetin alfa; dialysis; roxadustat; anemia patients ... See more keywords
Three-year safety observation of subcutaneous administration of epoetin-zeta in patients with chronic renal anemia: Results from PASCO II study
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DOI: 10.5414/cn110825
Abstract: Epoetin has been used to treat patients with renal anemia since 1988. Anti-erythropoietin antibody-mediated pure red cell aplasia (PRCA) has been associated with epoetin usage, and a PRCA incidence of 4.5 per 10,000 patient-years was… read more here.
Keywords: epoetin; safety; renal anemia; pasco study ... See more keywords