Articles with "epoxide" as a keyword



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Ceramic green and fired body with a uniform microstructure prepared using living characteristics of photo-curable cycloaliphatic epoxide: Applicability of cycloaliphatic epoxide in photo-polymerization-based 3D printing

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Published in 2021 at "Journal of the European Ceramic Society"

DOI: 10.1016/j.jeurceramsoc.2021.10.015

Abstract: Abstract In photopolymerization-based ceramic 3D printing, light cannot efficiently penetrate the opaque slurry, which is composed of particles and a photo-curable monomer. This can result in a difference of the crosslinking density within the layer,… read more here.

Keywords: photo curable; epoxide; body uniform; cycloaliphatic epoxide ... See more keywords
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Metabolic Activation of the Acrylamide Michael Acceptor Warhead in Futibatinib to an Epoxide Intermediate Engenders Covalent Inactivation of CYP3A

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Published in 2022 at "Drug Metabolism and Disposition"

DOI: 10.1124/dmd.122.000895

Abstract: Futibatinib (FUT) is a potent inhibitor of fibroblast growth factor receptor (FGFR) 1–4 that is currently under clinical investigation for intrahepatic cholangiocarcinoma. Unlike its predecessors, FUT possesses an acrylamide warhead, which enables it to bind… read more here.

Keywords: cyp3a; inactivation cyp3a; epoxide; covalent inactivation ... See more keywords

Misclassification of PfEH1 and PfEH2 as Epoxide Hydrolases

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Published in 2017 at "mBio"

DOI: 10.1128/mbio.00004-17

Abstract: In their recent article (1), Spillman and colleagues report the two Plasmodium falciparum proteins PfEH1 and PfEH2 to be two novel epoxide hydrolases with an atypical active-site architecture. We strongly believe that this conclusion is… read more here.

Keywords: hydrolase; pfeh1 pfeh2; epoxide; epoxide hydrolases ... See more keywords