Epoxide ring opening with alcohols using heterogeneous Lewis acid catalysts: Regioselectivity and mechanism
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2018.11.038
Abstract: Abstract Lewis acidic catalytic materials are investigated for the regioselective ring opening of epoxides with alcohols. For ring opening epichlorohydrin with methanol, the catalytic activity shows a strong dependence on the type of support and… read more here.
Keywords: beta; ring opening; epoxide ring; regioselectivity mechanism ... See more keywords
Development of magnetically retrievable spinel nanoferrites as efficient catalysts for aminolysis of epoxides with amines
Sign Up to like & getrecommendations! Published in 2019 at "Materials Chemistry and Physics"
DOI: 10.1016/j.matchemphys.2018.10.021
Abstract: Abstract Magnetically separable spinel nanoferrites (MFe2O4; M = Co, Ni, Cu and Zn) have been used as proficient catalysts for epoxide ring opening with amines. To study the effect of synthetic methodology on the catalytic activity, all… read more here.
Keywords: development magnetically; spinel nanoferrites; epoxide ring; magnetically retrievable ... See more keywords
Intramolecular epoxide ring opening cyclisation reactions involving guanidines
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2016.12.065
Abstract: The cyclisation of N-allyl- and N-homoallylguanidines using DMDO leading to the formation of novel 5- and 6-membered guanidine heterocycles is reported. Several of the products formed displayed weak inhibition of glycosidase enzymes. read more here.
Keywords: ring opening; epoxide ring; opening cyclisation; intramolecular epoxide ... See more keywords
Base-mediated synthesis of benzimidazole-fused 1,4-benzoxazepines via sequential intermolecular epoxide ring-opening/intramolecular SNAr reactions
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.152491
Abstract: Abstract We have developed a transition-metal-free, practical route to benzimidazole-fused 1,4-benzoxazepines. Operationally, the protocol involves a K2CO3-mediated intermolecular ring opening of terminal epoxides by 2-(2-fluorophenyl)benzimidazole, followed by an intramolecular nucleophilic aromatic substitution (SNAr) reaction of… read more here.
Keywords: fused benzoxazepines; benzimidazole; epoxide ring; snar ... See more keywords
Iminologous epoxide ring-closure
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04496j
Abstract: The discovery of new reactions enables chemists to attain a better understanding of fundamental chemical reactivity and push the boundaries of organic synthesis. Our understanding and manipulation of high-energy states such as reactive conformations, intermediates,… read more here.
Keywords: 320 320; epoxide ring; ring closure; iminologous epoxide ... See more keywords
Remarkable Influence of Cobalt Catalysis on Epoxide Ring-Opening with Sulfoxonium Ylides
Sign Up to like & getrecommendations! Published in 2017 at "Synthesis"
DOI: 10.1055/s-0036-1588814
Abstract: Cobalt demonstrates a remarkable ability to catalytically divert the course of epoxide to oxetane ring expansion via reaction with a sulfoxonium ylide. An expanded survey of transition-metal catalysts has confirmed that cobalt salts uniquely instead… read more here.
Keywords: ring opening; influence cobalt; cobalt; epoxide ring ... See more keywords