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H4SiW12O40-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides: An efficient synthesis of 3,4-disubstituted 1H-pyrazoles

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Published in 2021 at "Chinese Chemical Letters"

DOI: 10.1016/j.cclet.2021.08.037

Abstract: Abstract A simple and efficient method for the synthesis of pyrazoles through a silicotungstic acid (H4SiW12O40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been developed. Various epoxides/aldehydes were smoothly reacted with sulfonyl hydrazides to furnish… read more here.

Keywords: catalyzed cyclization; disubstituted pyrazoles; cyclization epoxides; sulfonyl hydrazides ... See more keywords