Epoxides as Precursors to 1-Hydroxymethyl Indolizidine and Pyrrolizidine
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DOI: 10.1055/s-0036-1588173
Abstract: Herein we describe the synthesis of 1-hydroxymethyl pyrrolizidine and indolizidine alkaloids from epoxy-tethered pyrrole precursors. Two titanium-based methods are evaluated for the construction of the bicyclic scaffold: the Lewis acid mediated cyclization developed by Tanis… read more here.
Keywords: hydroxymethyl indolizidine; pyrrolizidine; indolizidine pyrrolizidine; epoxides precursors ... See more keywords