Highly Diastereo- and Enantioselective Palladium-Catalyzed [3 + 2] Cycloaddition of Vinyl Epoxides and α,β-Unsaturated Ketones.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03386
Abstract: An asymmetric [3 + 2] cycloaddition reaction of vinyl epoxides with α,β-unsaturated ketones, the single activated electron-deficient alkenes, has been achieved under Pd-catalysis in excellent diastereo- and enantioselectivity. The utilities of the protocol are demonstrated… read more here.
Keywords: epoxides unsaturated; highly diastereo; cycloaddition; unsaturated ketones ... See more keywords