Effect of Temperature on the Kinetics of the Activation of Treosulfan and Hydrolytic Decomposition of Its Active Epoxy Derivatives.
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DOI: 10.1016/j.xphs.2017.05.033
Abstract: Treosulfan (TREO) is a prodrug applied in the treatment of ovarian cancer and a myeloablative conditioning prior to stem cell transplantation. A sequential activation of TREO to intermediate monoepoxide (S,S-EBDM) and then to (2S,3S)-1,2:3,4-diepoxybutane (S,S-DEB)… read more here.
Keywords: temperature; effect temperature; treosulfan; activation ... See more keywords
Antifeedant Potential of Geranylacetone and Nerylacetone and Their Epoxy-Derivatives against Myzus persicae (Sulz.)
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DOI: 10.3390/molecules27248871
Abstract: Geranylacetone and nerylacetone are natural sesquiterpenoids, which play various roles in plant-insect interactions, including the deterrent and repellent effects on herbivores. The structural modifications of natural compounds often change their biological activities. The aim of… read more here.
Keywords: geranylacetone nerylacetone; nerylacetone epoxy; epoxy derivatives; geranylacetone ... See more keywords