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DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer

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Published in 2022 at "Clinical Cancer Research"

DOI: 10.1158/1078-0432.ccr-21-1299

Abstract: Abstract Purpose: Although chemotherapies kill most cancer cells, stem cell–enriched survivors seed metastasis, particularly in triple-negative breast cancers (TNBC). TNBCs arise from and are enriched for tumor stem cells. Here, we tested if inhibition of… read more here.

Keywords: stem cell; dot1l; aldh1 aldh1; stem ... See more keywords