Articles with "equilibrative nucleoside" as a keyword



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Molecular Characterization of Equilibrative Nucleoside Transporters in the Rat Carotid Body and Their Regulation by Chronic Hypoxia.

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Published in 2018 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-319-91137-3_5

Abstract: The mammalian carotid body (CB) is the main peripheral arterial chemoreceptor organ that is excited by decreases in blood PO2 (hypoxia) and increases in blood PCO2/H+. An increase in CB afferent carotid sinus nerve (CSN)… read more here.

Keywords: chronic hypoxia; molecular characterization; hypoxia; carotid body ... See more keywords

Novel variants provide differential stabilisation of human equilibrative nucleoside transporter 1 states

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Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2022.970391

Abstract: Human equilibrative nucleoside transporters represent a major pharmaceutical target for cardiac, cancer and viral therapies. Understanding the molecular basis for transport is crucial for the development of improved therapeutics through structure-based drug design. ENTs have… read more here.

Keywords: equilibrative nucleoside; novel variants; human equilibrative; nucleoside transporter ... See more keywords