Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor
Sign Up to like & getrecommendations! Published in 2020 at "Nature Chemical Biology"
DOI: 10.1038/s41589-019-0457-5
Abstract: G-protein-coupled receptors (GPCRs) are seven-transmembrane proteins mediating cellular signals in response to extracellular stimuli. Although three-dimensional structures showcase snapshots that can be sampled in the process and nuclear magnetic resonance detects conformational equilibria, the mechanism… read more here.
Keywords: adrenoreceptor; equilibrium; activation; equilibrium underlying ... See more keywords