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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb336
Abstract: Background: Treatment of immunologically cold tumors is a major challenge. IL-12 can activates both innate and adaptive immunity to elicit strong antitumor immunity. Nevertheless, the poor pharmacokinetic and severe side effects of IL-12 limit the…
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Keywords:
micelles loading;
cold tumors;
eradicate cold;
sensitive polymeric ... See more keywords