Behçet’s disease risk-variant HLA-B51/ERAP1-Hap10 alters human CD8 T cell immunity
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DOI: 10.1136/ard-2022-222277
Abstract: Objectives The endoplasmic reticulum aminopeptidase (ERAP1) haplotype Hap10 encodes for a variant allotype of the endoplasmic reticulum (ER)-resident peptide-trimming aminopeptidase ERAP1 with low enzymatic activity. This haplotype recessively confers the highest risk for Behçet’s diseases… read more here.
Keywords: hla; cd8 cell; erap1 hap10; erap1 ... See more keywords