Discoidin domain receptor 1 regulates ErbB2/ErbB3 signaling in mammary epithelial cells
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DOI: 10.1002/1873-3468.14522
Abstract: The ErbB2 receptor tyrosine kinase plays a key role in mammary gland development. It forms large clusters which serve as signaling platforms for integration of extracellular information. The discoidin domain receptor (DDR) family are collagen… read more here.
Keywords: discoidin domain; domain receptor; erbb3 signaling; receptor ... See more keywords
ERBB2 and ERBB3 Growth Factor Receptors, Neuregulin-1, CD44 and Ki-67 Proliferation Index in Neurofibromatosis Type 1-associated Peripheral Nerve Sheath Tumors
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DOI: 10.21873/anticanres.15712
Abstract: Aim: To characterize the growth pattern and antigen profile of peripheral nerve sheaths tumors (PNST) in a large series of tumors obtained from patients with neurofibromatosis type 1 (NF1). Materials and Methods: Tissue micro-array technique… read more here.
Keywords: factor receptors; growth; proliferation index; pnst ... See more keywords
Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2017.7532
Abstract: Cisplatin (CDDP) and doxorubicin (DOX) are chemotherapeutic drugs that trigger apoptosis by inducing DNA-damage. A previous study using breast cancer cells demonstrated the negative feedback modulation of the epidermal growth factor receptor (EGFR) and receptor… read more here.
Keywords: erk p38; erbb2; thr 677; erbb2 erbb3 ... See more keywords