Articles with "erbb3 pathway" as a keyword



Photo by nci from unsplash

NRG1/ERBB3 Pathway Activation Induces Acquired Resistance to XPO1 Inhibitors

Sign Up to like & get
recommendations!
Published in 2020 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.mct-19-0977

Abstract: XPO1 inhibitors have shown promise in cancer treatment, but mechanisms of resistance to these drugs are not well understood. In this study, we established selective inhibitors of nuclear export (SINE)-resistant ovarian cancer cell lines from… read more here.

Keywords: xpo1 inhibitors; nrg1 erbb3; cancer; resistance ... See more keywords