Articles with "erbb4 dependent" as a keyword



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Abstract A19: Discovery and characterization of selective and nonselective inhibitors of ErbB4 signaling: Putative targeted melanoma therapeutics

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.mel2019-a19

Abstract: Introduction: Gain-of-function mutations in the gene that encodes the ErbB4 receptor tyrosine kinase have been found in a significant fraction of melanoma samples. Melanoma cell lines that harbor some of these mutations are dependent on… read more here.

Keywords: discovery; erbb4 dependent; melanoma; proliferation ... See more keywords