Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure–QTc in patients with advanced or refractory solid tumors
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03896-1
Abstract: To characterize the effect of erdafitinib on electrocardiogram (ECG) parameters and the relationship between erdafitinib plasma concentrations and QTc interval changes in patients with advanced or refractory solid tumors. Triplicate ECGs and continuous 12-lead Holter… read more here.
Keywords: qtc; ecg; analysis; effect ... See more keywords
Erdafitinib exerts the anticancer effect on urothelial carcinoma via induction of authophagy.
Sign Up to like & getrecommendations! Published in 2020 at "Die Pharmazie"
DOI: 10.1691/ph.2020.9911
Abstract: Erdafitinib has recently been approved for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma (UC). The current study aimed to evaluate whether erdafitinib inhibits the proliferation in UC via inducing authophagy.… read more here.
Keywords: showed erdafitinib; authophagy; urothelial carcinoma; cell ... See more keywords