An ERG enhancer-based reporter identifies leukemia cells with elevated leukemogenic potential driven by ERG-USP9X feed-forward regulation.
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DOI: 10.1158/0008-5472.can-18-3215
Abstract: Acute leukemia is a rapidly progressing blood cancer with low survival rates. Unfavorable prognosis is attributed to insufficiently characterized subpopulations of Leukemia Stem Cells (LSC) that drive chemoresistance and leukemia relapse. Here we utilized a… read more here.
Keywords: leukemia; enhancer based; based reporter; erg enhancer ... See more keywords