Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.05.001
Abstract: Xiaoju Wang, Yuanyuan Qiao, Irfan A. Asangani, Bushra Ateeq, Anton Poliakov, Marcin Cie slik, Sethuramasundaram Pitchiaya, Balabhadrapatruni V.S.K. Chakravarthi, Xuhong Cao, Xiaojun Jing, Cynthia X. Wang, Ingrid J. Apel, Rui Wang, Jean Ching-Yi Tien, Kristin… read more here.
Keywords: development peptidomimetic; erg gene; inhibitors erg; peptidomimetic inhibitors ... See more keywords
Gene of the month: ERG
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2022-208350
Abstract: The ERG gene belongs to the erythroblastosis transformation specific family of transcription factors and encodes for the transcription regulator protein ERG. It is located on chromosome 22q22 and is a nuclear transcription factor. In normal… read more here.
Keywords: gene month; transcription; month erg; gene ... See more keywords
An ERG Gene Analysis in Two Cases with Metastatic Castration-resistant Prostate Cancer in Which Abiraterone Demonstrated Long-term Efficacy
Sign Up to like & getrecommendations! Published in 2019 at "Internal Medicine"
DOI: 10.2169/internalmedicine.3302-19
Abstract: We analyzed the ERG gene status using fluorescence in situ hybridization (FISH) in two chemotherapy-naïve cases with metastatic castration-resistant prostate cancer (mCRPC) in which abiraterone demonstrated a long-term durable complete response. FISH identified Class 1… read more here.
Keywords: erg gene; gene; class edel; cases metastatic ... See more keywords
Significance of the TMPRSS2:ERG gene fusion in prostate cancer
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DOI: 10.3892/mmr.2017.7281
Abstract: The transmembrane protease serine 2:v-ets erythroblastosis virus E26 oncogene homolog (TMPRSS2:ERG) gene fusion is common in prostate cancer, while its functional role is not fully understood. The present study aimed to investigate the significance of… read more here.
Keywords: prostate; tmprss2 erg; erg gene; prostate cancer ... See more keywords