Myeloid sarcoma and extramedullary hematopoiesis expand the spectrum of ERG-positive proliferations; an ancillary tool in the diagnosis.
Sign Up to like & getrecommendations! Published in 2022 at "Human pathology"
DOI: 10.1016/j.humpath.2022.03.001
Abstract: AIMS ERG overexpression has been linked to acute myeloid leukemia/myelod sarcoma (MS). The aim of our study was to identify the frequency of ERG immunohistochemical (IHC) expression in MS (n= 21), blastic plasmacytoid dendritic cell… read more here.
Keywords: expression; erg positive; myeloid; sarcoma ... See more keywords
Abstract 4868: Targeting of ERG positive prostate cancers with ERGi-USU-6 salt derivative
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4868
Abstract: Introduction: Prostate cancer (PCa) is the second leading cause of cancer deaths among men in the United States. Approximately 50% of patients with PCa harbor an oncogenic TMPRRS2- ERG gene fusion in their primary tumor… read more here.
Keywords: ergi usu; prostate; erg positive; salt derivative ... See more keywords
Abstract B062: ERGi-USU selectively inhibit ERG positive prostate cancer through ATF3 mediated ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.prca2023-b062
Abstract: Introduction: Prostate cancer (PCa) is the second leading cause of cancer deaths among men in the United States. Approximately 50% of patients with PCa harbor an oncogenic TMPRRS2- ERG gene fusion in their primary and… read more here.
Keywords: ergi usu; prostate cancer; cancer; erg positive ... See more keywords
Identification of F-Box/SPRY Domain-Containing Protein 1 (FBXO45) as a Prognostic Biomarker for TMPRSS2–ERG-Positive Primary Prostate Cancers
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DOI: 10.3390/cancers15061890
Abstract: Simple Summary FBXO45 plays a role in the regulation of apoptosis through the ubiquitylation and degradation of specific target proteins. While FBXO45 has been suggested to have prognostic potential in various cancers, its specific role… read more here.
Keywords: pca; tmprss2 erg; expression; erg positive ... See more keywords
ALDH3A2, ODF2, QSOX2, and MicroRNA-503-5p Expression to Forecast Recurrence in TMPRSS2-ERG-Positive Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911695
Abstract: Following radical surgery, patients may suffer a relapse. It is important to identify such patients so that therapy tactics can be modified appropriately. Existing stratification schemes do not display the probability of recurrence with enough… read more here.
Keywords: prostate cancer; aldh3a2 odf2; erg positive; tmprss2 erg ... See more keywords