Detection of antifungal drug-resistant and ERG11 gene mutations among clinical isolates of Candida species isolated from Khartoum, Sudan.
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DOI: 10.12688/f1000research.24854.1
Abstract: Background: Candida species are one of the most important opportunistic fungal pathogens that cause both superficial and systemic infections, especially in immunocompromised individuals. Considering the sharp increase in the rate of Candida infections, and resistance to commonly… read more here.
Keywords: erg11 gene; resistance; clinical isolates; among clinical ... See more keywords
A New Variant of Mutational and Polymorphic Signatures in the ERG11 Gene of Fluconazole-Resistant Candida albicans
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DOI: 10.2147/idr.s360973
Abstract: Background Resistance to antifungal drugs for treating Candida infections remains a major concern globally despite the range of medications available. Most of these drugs target key proteins essential to the life cycle of the organism.… read more here.
Keywords: erg11 gene; candida species; candida; resistance ... See more keywords
The A756T Mutation of the ERG11 Gene Associated With Resistance to Itraconazole in Candida Krusei Isolated From Mycotic Mastitis of Cows
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DOI: 10.3389/fvets.2021.634286
Abstract: Candida krusei (C. krusei) has been recently recognized as an important pathogen involved in mycotic mastitis of cows. The phenotypic and molecular characteristics of 15 C. krusei clinical isolates collected from cows with clinical mastitis… read more here.
Keywords: mastitis; itraconazole; itraconazole resistant; krusei ... See more keywords
Lack of Association between Fluconazole Susceptibility and ERG11 Nucleotide Polymorphisms in Cryptococcus neoformans Clinical Isolates from Uganda
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DOI: 10.3390/jof8050508
Abstract: Fluconazole is the drug of choice for cryptococcal meningitis (CM) monoprophylaxis in resource-limited settings such as Uganda. Emerging fluconazole resistance linked to mutations in the Cryptococcus neoformans ERG11 gene (CYP51) has been observed in clinical… read more here.
Keywords: clinical isolates; erg11 gene; neoformans clinical; nucleotide polymorphisms ... See more keywords