Articles with "erg24" as a keyword



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The sterol C-14 reductase Erg24 is responsible for ergosterol biosynthesis and ion homeostasis in Aspergillus fumigatus.

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Published in 2021 at "Applied microbiology and biotechnology"

DOI: 10.1007/s00253-021-11104-5

Abstract: Ergosterol, a major lipid present in the fungal cell membrane, is considered as an effective antifungal drug target. A rational strategy for increasing drug reservoir relies on functionally validation of essential enzymes involved in fungal… read more here.

Keywords: ion homeostasis; fumigatus; ergosterol biosynthesis; erg24 ... See more keywords