Articles with "ergosterol" as a keyword



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Impact of ergosterol content on acetic and lactic acids toxicity to Saccharomyces cerevisiae

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Published in 2022 at "Yeast"

DOI: 10.1002/yea.3828

Abstract: Organic acid stress often represents a major hurdle in industrial bio‐based microbial processes. Organic acids can be released from lignocellulosic feedstocks pretreatment and can also be desirable products obtained by microbial fermentation with applications in… read more here.

Keywords: ergosterol; impact ergosterol; ergosterol content; organic acids ... See more keywords
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Evaluation of ergosterol composition and esterification rate in fungi isolated from mangrove soil, long-term storage of broken spores, and two soils

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Published in 2020 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-020-10601-3

Abstract: Abstract Ergosterol is an important fungal-specific biomarker, but its use for fungal biomass estimation is still varied. It is important to distinguish between free and esterified ergosterols, which are mainly located on the plasma membrane… read more here.

Keywords: ergosterol; esterification rate; esterification; ergosterol esterification ... See more keywords
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Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol

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Published in 2020 at "Journal of Natural Medicines"

DOI: 10.1007/s11418-020-01419-4

Abstract: We previously revealed that Choreito, a traditional Kampo medicine, strongly inhibits bladder carcinogenesis promotion. We have also shown that Polyporus sclerotium, which is one of the crude drugs in Choreito, has the strongest bladder carcinogenesis… read more here.

Keywords: ergosterol; bladder carcinogenesis; effect; brassicasterol ... See more keywords
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Recent Advances in Ergosterol Biosynthesis and Regulation Mechanisms in Saccharomyces cerevisiae

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Published in 2017 at "Indian Journal of Microbiology"

DOI: 10.1007/s12088-017-0657-1

Abstract: Ergosterol, an important component of the fungal cell membrane, is not only essential for fungal growth and development but also very important for adaptation to stress in fungi. Ergosterol is also a direct precursor for… read more here.

Keywords: biosynthesis regulation; ergosterol biosynthesis; biosynthesis; ergosterol ... See more keywords

Interaction of amphotericin B and saturated or unsaturated phospholipid monolayers containing cholesterol or ergosterol at the air-water interface.

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Published in 2019 at "Biophysical chemistry"

DOI: 10.1016/j.bpc.2019.106317

Abstract: The antimicrobial activity of amphotericin B (AmB) depends on its interaction with ergosterol-containing cell membranes of fungus. Cholesterol is a sterol in mammalian cell membrane, and its structure is very similar to ergosterol, which caused… read more here.

Keywords: ergosterol; monolayer; ergosterol monolayer; interaction ... See more keywords
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Effect of ergosterol on the fungal membrane properties. All-atom and coarse-grained molecular dynamics study.

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Published in 2017 at "Chemistry and physics of lipids"

DOI: 10.1016/j.chemphyslip.2017.11.006

Abstract: Cell membranes are complex multicomponent systems consisting of thousands of different lipids with numerous embedded membrane proteins and many types of sterols. We used all-atom and coarse-grained molecular dynamics simulations to study the structural and… read more here.

Keywords: ergosterol; molecular dynamics; grained molecular; coarse grained ... See more keywords
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Glycyrrhizic acid attenuates growth of Leishmania donovani by depleting ergosterol levels

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Published in 2017 at "Experimental Parasitology"

DOI: 10.1016/j.exppara.2017.02.015

Abstract: Abstract In the present study, glycyrrhizic acid (GA) the main component of Glycyrrhiza glabra was evaluated for its efficacy as antileishmanial agent and its mode of action explored. GA inhibits promastigotes and intracellular amastigotes in… read more here.

Keywords: growth; ergosterol; glycyrrhizic acid; ergosterol levels ... See more keywords
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Ultrasound-assisted extraction of ergosterol and antioxidant components from mushroom by-products and the attainment of a β-glucan rich residue.

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Published in 2020 at "Food chemistry"

DOI: 10.1016/j.foodchem.2020.127390

Abstract: Revalorization of mushroom by-product (stalks of A. bisporus) by extracting its components is proposed. The extraction kinetics at 25 °C of ergosterol, phenolic compounds and antioxidant activity by mechanical agitation (at 130 rpm) and ultrasound assistance (at… read more here.

Keywords: extraction; antioxidant activity; ergosterol; mushroom ... See more keywords
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Phase Separation in Liposomes Determined by Ergosterol and Classified Using Machine Learning

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Published in 2022 at "Microscopy and Microanalysis"

DOI: 10.1017/s1431927622012521

Abstract: Abstract Recent studies indicated that ergosterol (Erg) helps form strongly ordered lipid domains in membranes that depend on their chemical characters. However, direct evidence of concentration-dependent interaction of Erg with lipid membranes has not been… read more here.

Keywords: phase separation; ergosterol; separation; machine learning ... See more keywords
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Periconiastone A, an Antibacterial Ergosterol with a Pentacyclo[8.7.0.01,5.02,14.010,15]heptadecane System from Periconia sp. TJ403-rc01.

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Published in 2019 at "Organic letters"

DOI: 10.1021/acs.orglett.9b03270

Abstract: Periconiastone A (1), an ergosterol with an unprecedented pentacyclo[8.7.0.01,5.02,14.010,15]heptadecane system, was isolated from Periconia sp. TJ403-rc01. Its structure was assigned by extensive spectroscopic analyses and quantum-chemical 13C NMR and ECD calculations. A vinylogous α-ketol rearrangement… read more here.

Keywords: pentacyclo 010; ergosterol; heptadecane system; 010 heptadecane ... See more keywords
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Antifungal drug testing by combining minimal inhibitory concentration testing with target identification by gas chromatography–mass spectrometry

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Published in 2017 at "Nature Protocols"

DOI: 10.1038/nprot.2017.005

Abstract: Fungal infections and their increasing resistance to antibiotics are an emerging threat to public health. Novel antifungal drugs, as well technologies that can help us bolster the antimicrobial pipeline and understand resistance mechanisms, are needed.… read more here.

Keywords: gas chromatography; ergosterol; mass; target ... See more keywords