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   Articles with "ergosterol" as a keyword



Otilonium Bromide Exhibits Potent Antifungal Effects by Blocking Ergosterol Plasma Membrane Localization and Triggering Cytotoxic Autophagy in Candida Albicans

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202406473

Abstract: Candidiasis, which presents a substantial risk to human well‐being, is frequently treated with azoles. However, drug‐drug interactions caused by azoles inhibiting the human CYP3A4 enzyme, together with increasing resistance of Candida species to azoles, represent… read more here.

Keywords: cytotoxic autophagy; membrane localization; ergosterol; drug ... See more keywords

Volatilome of the maize phytopathogenic fungus Fusarium verticillioides: potential applications in diagnosis and biocontrol.

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recommendations! Published in 2024 at "Pest management science"

DOI: 10.1002/ps.8439

Abstract: BACKGROUND Fusarium verticillioides is a maize fungal phytopathogen and a producer of volatile organic compounds (VOCs) and fumonisin B1 (FB1). Our aim was to study the volatilome, conidial production, ergosterol and FB1 biosynthesis in maize… read more here.

Keywords: dpi; biocontrol; fusarium; ergosterol ... See more keywords

Impact of ergosterol content on acetic and lactic acids toxicity to Saccharomyces cerevisiae

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recommendations! Published in 2022 at "Yeast"

DOI: 10.1002/yea.3828

Abstract: Organic acid stress often represents a major hurdle in industrial bio‐based microbial processes. Organic acids can be released from lignocellulosic feedstocks pretreatment and can also be desirable products obtained by microbial fermentation with applications in… read more here.

Keywords: ergosterol; impact ergosterol; ergosterol content; organic acids ... See more keywords

Evaluation of ergosterol composition and esterification rate in fungi isolated from mangrove soil, long-term storage of broken spores, and two soils

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recommendations! Published in 2020 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-020-10601-3

Abstract: Abstract Ergosterol is an important fungal-specific biomarker, but its use for fungal biomass estimation is still varied. It is important to distinguish between free and esterified ergosterols, which are mainly located on the plasma membrane… read more here.

Keywords: ergosterol; esterification rate; esterification; ergosterol esterification ... See more keywords

Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol

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recommendations! Published in 2020 at "Journal of Natural Medicines"

DOI: 10.1007/s11418-020-01419-4

Abstract: We previously revealed that Choreito, a traditional Kampo medicine, strongly inhibits bladder carcinogenesis promotion. We have also shown that Polyporus sclerotium, which is one of the crude drugs in Choreito, has the strongest bladder carcinogenesis… read more here.

Keywords: ergosterol; bladder carcinogenesis; effect; brassicasterol ... See more keywords

Recent Advances in Ergosterol Biosynthesis and Regulation Mechanisms in Saccharomyces cerevisiae

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recommendations! Published in 2017 at "Indian Journal of Microbiology"

DOI: 10.1007/s12088-017-0657-1

Abstract: Ergosterol, an important component of the fungal cell membrane, is not only essential for fungal growth and development but also very important for adaptation to stress in fungi. Ergosterol is also a direct precursor for… read more here.

Keywords: biosynthesis regulation; ergosterol biosynthesis; biosynthesis; ergosterol ... See more keywords

Interaction of amphotericin B and saturated or unsaturated phospholipid monolayers containing cholesterol or ergosterol at the air-water interface.

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recommendations! Published in 2019 at "Biophysical chemistry"

DOI: 10.1016/j.bpc.2019.106317

Abstract: The antimicrobial activity of amphotericin B (AmB) depends on its interaction with ergosterol-containing cell membranes of fungus. Cholesterol is a sterol in mammalian cell membrane, and its structure is very similar to ergosterol, which caused… read more here.

Keywords: ergosterol; monolayer; ergosterol monolayer; interaction ... See more keywords

Effect of ergosterol on the fungal membrane properties. All-atom and coarse-grained molecular dynamics study.

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recommendations! Published in 2017 at "Chemistry and physics of lipids"

DOI: 10.1016/j.chemphyslip.2017.11.006

Abstract: Cell membranes are complex multicomponent systems consisting of thousands of different lipids with numerous embedded membrane proteins and many types of sterols. We used all-atom and coarse-grained molecular dynamics simulations to study the structural and… read more here.

Keywords: ergosterol; molecular dynamics; grained molecular; coarse grained ... See more keywords

Glycyrrhizic acid attenuates growth of Leishmania donovani by depleting ergosterol levels

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recommendations! Published in 2017 at "Experimental Parasitology"

DOI: 10.1016/j.exppara.2017.02.015

Abstract: Abstract In the present study, glycyrrhizic acid (GA) the main component of Glycyrrhiza glabra was evaluated for its efficacy as antileishmanial agent and its mode of action explored. GA inhibits promastigotes and intracellular amastigotes in… read more here.

Keywords: growth; ergosterol; glycyrrhizic acid; ergosterol levels ... See more keywords
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Ultrasound-assisted extraction of ergosterol and antioxidant components from mushroom by-products and the attainment of a β-glucan rich residue.

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recommendations! Published in 2020 at "Food chemistry"

DOI: 10.1016/j.foodchem.2020.127390

Abstract: Revalorization of mushroom by-product (stalks of A. bisporus) by extracting its components is proposed. The extraction kinetics at 25 °C of ergosterol, phenolic compounds and antioxidant activity by mechanical agitation (at 130 rpm) and ultrasound assistance (at… read more here.

Keywords: extraction; antioxidant activity; ergosterol; mushroom ... See more keywords

Phase Separation in Liposomes Determined by Ergosterol and Classified Using Machine Learning

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recommendations! Published in 2022 at "Microscopy and Microanalysis"

DOI: 10.1017/s1431927622012521

Abstract: Abstract Recent studies indicated that ergosterol (Erg) helps form strongly ordered lipid domains in membranes that depend on their chemical characters. However, direct evidence of concentration-dependent interaction of Erg with lipid membranes has not been… read more here.

Keywords: phase separation; ergosterol; separation; machine learning ... See more keywords