Articles with "ergosterol biosynthesis" as a keyword



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Synergistic interactions between a variety of insecticides and an ergosterol biosynthesis inhibitor fungicide in dietary exposures of bumble bees (Bombus terrestris L.).

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Published in 2018 at "Pest management science"

DOI: 10.1002/ps.4756

Abstract: BACKGROUND In recent years, concern has been raised over honey bee colony losses, and also among wild bees there is evidence for extinctions and range contractions in Europe and North America. Pesticides have been proposed… read more here.

Keywords: ergosterol biosynthesis; bombus terrestris; toxicity; biosynthesis inhibitor ... See more keywords
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The sterol C-14 reductase Erg24 is responsible for ergosterol biosynthesis and ion homeostasis in Aspergillus fumigatus.

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Published in 2021 at "Applied microbiology and biotechnology"

DOI: 10.1007/s00253-021-11104-5

Abstract: Ergosterol, a major lipid present in the fungal cell membrane, is considered as an effective antifungal drug target. A rational strategy for increasing drug reservoir relies on functionally validation of essential enzymes involved in fungal… read more here.

Keywords: ion homeostasis; fumigatus; ergosterol biosynthesis; erg24 ... See more keywords
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Recent Advances in Ergosterol Biosynthesis and Regulation Mechanisms in Saccharomyces cerevisiae

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Published in 2017 at "Indian Journal of Microbiology"

DOI: 10.1007/s12088-017-0657-1

Abstract: Ergosterol, an important component of the fungal cell membrane, is not only essential for fungal growth and development but also very important for adaptation to stress in fungi. Ergosterol is also a direct precursor for… read more here.

Keywords: biosynthesis regulation; ergosterol biosynthesis; biosynthesis; ergosterol ... See more keywords
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Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds.

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Published in 2020 at "Food research international"

DOI: 10.1016/j.foodres.2019.108930

Abstract: The influence of antifungal tetraconazole residues (either as an active substance or as a commercial formulation product) on the fermentative activity of Saccharomyces cerevisiae yeast was evaluated in pasteurized Garnacha red must by using laboratory-scale… read more here.

Keywords: ergosterol biosynthesis; alters methionine; methionine ergosterol; tetraconazole alters ... See more keywords
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Traditionally practiced medicinal plant extracts inhibit the ergosterol biosynthesis of clinically isolated dermatophytic pathogens.

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Published in 2018 at "Journal de mycologie medicale"

DOI: 10.1016/j.mycmed.2017.11.001

Abstract: OBJECTIVE Dermatophytes are resistant to some available antibiotics. Development of new plant drugs to control drug resistant microbes is urgently needed. This study evaluates the antidermatophytic potential of 18 selected medicinal plants used by traditional… read more here.

Keywords: ergosterol biosynthesis; plant; ethanol extract; phyllanthus ... See more keywords
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Identification of a consensus motif in Erg28p required for C-4 demethylation in yeast ergosterol biosynthesis based on mutation analysis.

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Published in 2018 at "FEMS microbiology letters"

DOI: 10.1093/femsle/fny002

Abstract: The Erg28p protein is localized to the endoplasmic reticulum, where it acts as a scaffold to tether the C-4 demethylase complex involved in the sterol biosynthesis pathway of Saccharomyces cerevisiae. However, due to the challenges… read more here.

Keywords: biosynthesis; ergosterol biosynthesis; consensus motif; erg28p required ... See more keywords
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Transcriptional regulation of ergosterol biosynthesis genes in response to iron deficiency

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Published in 2022 at "Environmental Microbiology"

DOI: 10.1111/1462-2920.16157

Abstract: Abstract Iron participates as an essential cofactor in the biosynthesis of critical cellular components, including DNA, proteins and lipids. The ergosterol biosynthetic pathway, which is an important target of antifungal treatments, depends on iron in… read more here.

Keywords: ergosterol biosynthesis; iron; iron deficiency;
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Combining transcriptomics and metabolomics to reveal the underlying molecular mechanism of ergosterol biosynthesis during the fruiting process of Flammulina velutipes

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Published in 2019 at "BMC Genomics"

DOI: 10.1186/s12864-019-6370-1

Abstract: BackgroundFlammulina velutipes has been recognized as a useful basidiomycete with nutritional and medicinal values. Ergosterol, one of the main sterols of F. velutipes is an important precursor of novel anticancer and anti-HIV drugs. Therefore, many… read more here.

Keywords: ergosterol biosynthesis; biosynthesis; molecular mechanism; fruiting bodies ... See more keywords

The genome and transcriptome of Sarocladium terricola provide insight into ergosterol biosynthesis

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Published in 2023 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2023.1181287

Abstract: Sarocladium terricola is a species of ascomycete fungus that has been recognized as a biocontrol agent for managing animal and plant pathogens, and exhibits significant potential as a feed additive. In this study, we utilized… read more here.

Keywords: ergosterol biosynthesis; terricola; sarocladium terricola;
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Voriconazole Treatment Induces a Conserved Sterol/Pleiotropic Drug Resistance Regulatory Network, including an Alternative Ergosterol Biosynthesis Pathway, in the Clinically Important FSSC Species, Fusarium keratoplasticum

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Published in 2022 at "Journal of Fungi"

DOI: 10.3390/jof8101070

Abstract: Fusarium keratoplasticum is the Fusarium species most commonly associated with human infections (fusariosis). Antifungal treatment of fusariosis is often hampered by limited treatment options due to resistance towards azole antifungals. The mechanisms of antifungal resistance… read more here.

Keywords: ergosterol biosynthesis; treatment; biosynthesis; drug resistance ... See more keywords